Committee

James MacRae (The Francis Crick Institute, LMN President; email james.macrae@crick.ac.uk)

James completed a PhD on structural glycobiology in trypanosomatid parasites at the University of Dundee, before moving to the University of Melbourne in 2006. Here, he expanded these interests into developing novel techniques in order to study the metabolism of apicomplexan parasites, including Toxoplasma gondii and the malaria parasite, Plasmodium falciparum. Since 2013, James has been of Head of Metabolomics at The Francis Crick Institute (formerly the National Institute for Medical Research) in central London. He specialises in targeted techniques and is developing new tools for metabolomics research in a number of areas (including GC-MS, LC-MS, stable isotope labelling, and lipidomics), while maintaining interests in host-parasite metabolism.

Tim Ebbels (Imperial, LMN Secretary)

Tim is a lapsed astrophysicist who now spends his time delving into the mysteries of big biomedical data. His particular interests lie in how statistical and machine learning techniques can improve information recovery in omics. He works primarily with metabolomics, from raw data processing through multivariate modelling, to data integration, pathway and network analysis.

Olivia Corcoran (University of East London, LMN Treasurer)

Olivia Corcoran is Professor of Bioanalytical Chemistry in the School of Health, Sport and Bioscience at the University of East London. She leads the Medicines Research Group focusing on quality, safety and efficacy of pharmaceutical and phytomedicines.  Olivia has worked at Pfizer Central Research, Imperial College London, Glaxo Group Research, Bruker BioSpin and King’s College London.  She has expertise in developing novel flow technologies to further drug discovery.

Hector Keun (Imperial College London)

Hector is a biochemist with an interest in applying metabolomics and integrative bioinformatics to tackle problems in oncology and toxicology.  He joined Imperial in 2001 after completing a DPhil in structural biology and now leads the Cancer Metabolism & Systems Toxicology group based in the Division of Cancer.   His current work includes the development of metabolic therapies for cancer treatment, exploring metabolic regulation in tumour cells by microRNAs and the identification of prognostic and predictive biomarkers.  Find out more at https://www.imperial.ac.uk/people/h.keun

Anisha Wijeyesekera (University of Reading)

Anisha completed a PhD in NMR-based metabolic phenotyping at Imperial College London. She joined the University of Reading in 2016 as a lecturer in the Food Microbial Sciences Unit, where her research is focussed on the application of analytical technologies for functional assessment of the microbiome, and furthering understanding of host-gut interactions.

Ruey-Leng Loo (University of Kent)

Ruey-Leng is a senior lecturer at the Medway School of Pharmacy. She completed a PhD on metabolome wide association study in Imperial College London, before starting her academic career in University of Kent.  Her main research focuses on the discovery of metabolic biomarkers of cardiovascular diseases in large scale human population studies.  She also investigates the effects of diets and physical activities on health.

Christina Legido-Quigley (King’s College London/Steno Diabetes Center Copenhagen, DK)

Cristina Legido-Quigley is a PI in Systems Medicine at Steno Diabetes Center Copenhagen and in King’s College London. She fell in love with analytical chemistry after working in SmithKline Beecham in the 90s. In 2004 she received a PhD in nanoLC-MS at Imperial College London and moved towards applying LC-MS in metabolomics in 2006. Her current work focuses on brain- liver diseases & she has several projects in the clinic, such as the stratification of patients with diabetes and clinical trials in dementia.

Volker Behrends (University of Roehampton)

Volker is a biologist working at the interface of microbiology and analytical chemistry with interest in bacterial metabolism, evolution and infection. Using metabolomics technique coupled, he aims to understand the role of bacterial metabolism in health and disease and how the metabolism is influenced by the cell’s surroundings.

Florence Raynaud (The Institute of Cancer Research)

Florence Raynaud is a pharmacologist involved in preclinical and clinical development of novel anticancer agents. She is responsible for the drug metabolism and pharmacokinetics activities in the Cancer Therapeutic Unit at the Institute of Cancer Research and in Phase I clinical studies at the Royal Marsden Hospital. Her team is particularly interested in identifying and measuring metabolite biomarkers by LCMS to support drug development in oncology.

Toby Athersuch (Imperial College, LMN Website)

Toby is a Lecturer in Environmental Toxicology & Biomarkers at Imperial. His main reserach interests lie in the application of NMR and MS-based metabolic phenotyping in large-scale exposome projects to help understand the links between environmental exposures and human health outcomes.

 

Former Committee Members